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What does our department do?

Education

The Human Genetics department contributes to the organization and teaching of regular education in the Bachelor's and Master's programs in the field of study 'Medicine' and 'Biomedical Sciences'. Particularly in the fields:

• Medical-, neuro- and tumor genetics;
• Metabolic Syndromes;
• Radiation and bioinformatics.

Members of the department are involved in organizing and/or teaching for various educational blocks, FOS courses and minors. The department is also widely represented in committees overarching other blocks. In addition, there is a high level of participation in many extra-curricular educational activities, for example, the department gives lectures at other universities and colleges. Post-academic education is also organized, especially within the Graduate School Medical Genetics Center South-West Netherlands (MGC).

The Human Genetics department contributes to the organization and teaching of regular education in the Bachelor's and Master's programs in the field of study 'Medicine' and 'Biomedical Sciences'. Particularly in the fields:

• Medical-, neuro- and tumor genetics;
• Metabolic Syndromes;
• Radiation and bioinformatics.

Members of the department are involved in organizing and/or teaching for various educational blocks, FOS courses and minors. The department is also widely represented in committees overarching other blocks. In addition, there is a high level of participation in many extra-curricular educational activities, for example, the department gives lectures at other universities and colleges. Post-academic education is also organized, especially within the Graduate School Medical Genetics Center South-West Netherlands (MGC).

The department has an education committee. The education coordinator of the department is mr. prof.dr.ir. J.A.P. (Ko) Willems van Dijk.

Training courses

Researchers in Training (OIO)

Research internships

Within the Human Genetics department there are various internship opportunities for students of Medicine, Biomedical Sciences, Life Science and Technology, or from similar HLO and other university courses. In addition, there are sporadically internships available for students from MLO courses. Information about the various research topics within the department can be found under 'Research'.

For more information and availability of internships, please contact the secretariat of the Human Genetics department. Send your CV and motivation letter to: , stating the period in which you would like to do an internship.

Researchers in Training (OIO)

The department has an average of 35 to 40 PhD students in training.

Research

The Human Genetics department is a broadly oriented research department, zooming in on the (epi)genetic aspects of monogenous, multifactorial, and acquired diseases. Translating basic scientific findings into clinical relevance is pivotal to the department's translational focus.

It has longstanding and intense collaborations worldwide and principal investigators of Human Genetics are involved as coordinator of or participant in several national and international initiatives.

Research programmes

The department's organizational structure is based on biological themes, interconnected by common technological and biological approaches.

The main areas of interest are:

• Neuromuscular and neurological genetics (muscle dystrophies, neurodegenerative diseases, migraine);
• Oncogenetics (breast and bowel cancer, paragangliomas);
• Genomic instability, toxicogenomics, DNA-damage and mutagenesis;
• Immunogenetics; epigenetics (repeats, primary immunodeficiencies, cancer);
• Population genetics (including forensic genetics and archaeogenetics);
• Metabolic genetics;
• Developmental genetics, especially renal diseases.

The department's organizational structure is based on biological themes, interconnected by common technological and biological approaches.

The main areas of interest are:

• Neuromuscular and neurological genetics (muscle dystrophies, neurodegenerative diseases, migraine);
• Oncogenetics (breast and bowel cancer, paragangliomas);
• Genomic instability, toxicogenomics, DNA-damage and mutagenesis;
• Immunogenetics; epigenetics (repeats, primary immunodeficiencies, cancer);
• Population genetics (including forensic genetics and archaeogenetics);
• Metabolic genetics;
• Developmental genetics, especially renal diseases.

The connecting technologies are:

• Genome technology (genomics and transcriptomics);
• Bioinformatics and biosemantics;
• Genetic therapy;
• Animal models;
• Biobanking.

Research performed in the department is clustered in four LUMC research programmes and is host to several Technology Platforms and Facilities. Click on the links below for more information about the research programmes, the individual research groups and the Technology Platforms and Facilities.

The department is host to many PhD students from all around the world. The staff members provides education within the fields of Medicine and Biomedical Sciences and contribute to postgraduate and extra-curricular education both within and outside the LUMC.

Patient care is not carried out directly by the department. Patient-related tasks, often of a diagnostic nature, are largely carried out through close collaboration with Clinical Genetics and other departments within the LUMC.

Research groups

Research performed in the department is clustered in four LUMC research programs and is host to several Technology Platforms and Facilities. The department is organized in different research groups, Technology Platforms and Facilities.

Address

LUMC - Human Genetics

Postzone S-4-P

Postbus 9600

2300 RC Leiden

Visiting address

Einthovenweg 20

2333 ZC Leiden

Education coordination

Prof.dr.ir. Ko (J.A.P) Willems van Dijk

Phone:

E-mail:

Office: S-3-40